Elizabeth Byrne has been seen as Senta in with Portland Opera, Arizona Opera, Austin Lyric Opera, and the Boston Symphony Orchestra under the baton of Maestro James Levine. In operas from Wagner's she has been seen as Brünnhilde in with the Staatstheater Stuttgart, Brünnhilde in at the Austin Lyric Opera, Sieglinde in concert with the Knoxville Symphony Orchestra, as well as Gutrune and Gerhilde in the Lyric Opera of Chicago's first complete conducted by Zubin Mehta.
Ms. Byrne has also covered the roles of both Brnnhilde in and Leonora in at the Metropolitan Opera, as well as Isolde in Wagner's for San Francisco Opera. At the Metropolitan Opera she has been seen as The Duchess of Parma in Busoni's and the Fourth Maid in and at the Lyric Opera of Chicago she performed the role of the Overseer in the Gtz Friedrich production of . Most recently Ms. Byrne was seen as the Witch in with Indianapolis Opera, after previously having sung the Mother with the Phoenix Symphony.
An excellent musician, Ms. Byrne is noted for her performances of contemporary operas having sung the world premiere performances of the role of Blanca in James MacMillan's opera at the Edinburgh Festival. The work was also performed in Glasgow and in Oporto, Portugal. Jonathan Moore directed the Scottish Opera production, which was broadcast on BBC-TV. In concert, Ms. Byrne has performed Mahler's at Royal Albert Hall and Shostakovich's at Canada's National Arts Centre. She made her Avery Fisher Hall debut performing Zemlinsky's rarely-heard with Leon Botstein and the American Symphony Orchestra. She has performed the Verdi with the Alabama Symphony and the Greensboro Symphony, Beethoven's with the symphony orchestras of Utah, Seattle, Richmond, and South Bend Symphony.